EM16: Nutrition: Biomolecular, pathophysiological, clinical and socio-health aspects

Research group made up of medical and nursing professionals belonging to the University of Cádiz, INiBICA and the Andalusian Health Service. The members of the group carry out academic and welfare activities. The latter both in the hospital setting and in primary care. The lines of research are focused on clinical research and the immediate practical application of the conclusions derived from the results of their research. In the last five years, four members of the group have defended their doctoral thesis. The ability to attract resources and disseminate the results of the different lines of research has increased in recent years.

• Mª José Santi Cano:
• E-mail: mariajose.santi@uca.es.
• ORCID: 0000-0002-4430-6031.

• Intervention studies on lifestyle and therapeutic adherence as an instrument to achieve an improvement in clinical evolution.
• Nutrition in the elderly: Analyze the influence of nutritional status on the clinical evolution of the elderly and the factors involved.
• Prothrombotic risk markers: To evaluate the association of central adiposity with cost-effective hemostatic markers and traditional cardiovascular risk factors in order to improve prevention and intervention. Cardiovascular risk biomarkers.
• Cardiovascular risk factors: Evaluation, prevention, control and treatment of cardiovascular risk factors.
• Use of information and communication technologies in the prevention and control of chronic diseases through mobile devices.
• Obesity and metabolic syndrome: Evaluation, prevention, control and treatment: Evaluation of the control of excess body weight in primary care. Influence of obesity and the clinical evolution of patients.
• Diabetes education: Evaluation of education in patients with type 2 diabetes mellitus as an instrument to achieve good metabolic control and improve adherence to therapeutic prescription.

Nutrition Cardiovascular risk factors Obesity Mellitus diabetes Mobile applications in health

• Principal Investigators:
  • Mª José Santi Cano (PI).
• Postdoctoral Researchers:
  • Mª Ángeles Bernal Jiménez.
  • José Carlos Rodríguez Bocanegra.
  • Mª del Carmen de la Fuente Coria.
  • Nuria Trujillo Garrido.
• Predoctoral Researchers:
  • Mª Ángeles Manzano Felipe.
  • Enrique Rivieccio Cecchettani.

• Ministerio De Ciencia E Innovación. Convocatoria 2019. PID2019-107229RA-100. PI: Marta Lima. Collaboration. Alerta cannabis: Evaluación de una intervención a medida basada en el ordenador para la prevención del consumo de cannabis en adolescentes de 14 a 18 años.

• Iniciativa Territorial Integrada (ITI) 2014-2020 para la provincia de Cádiz, por la Consejería de Salud y por el Fondo Europeo de Desarrollo Regional ITI-0014-2019 PI: Mª José Santi Cano. Prevención del sobrepeso y la obesidad infantil en escolares de la provincia de Cádiz. Impacto de una aplicación web en la mejora de la adherencia al programa de rehabilitación cardiaca, estilo de vida y control de los factores de riesgo cardiovascular.
• Consejería de Salud y Familias, Junta de Andalucía, PI-0067-2018. PI: Mª José Santi Cano. Ensayo clínico controlado aleatorizado de intervención en estilo de vida y adherencia terapéutica tras evento coronario basado en aplicación web interactiva.
• Iniciativa Territorial Integrada (ITI) 2014-2020 para la provincia de Cádiz, por la Consejería de Salud y por el Fondo Europeo de Desarrollo Regional PI-0007-2017 Collaboration. Prevención del sobrepeso y la obesidad infantil en escolares de la provincia de Cádiz. Estudio cuasi-experimental de la efectividad de una intervención multi-componente.

1. María Ángeles Bernal-Jiménez, Germán Calle-Pérez, Alejandro Gutiérrez-Barrios, Livia Gheorghe, Ana María Solano-Mulero, Amelia Rodríguez-Martín, Josep A. Tur, Rafael Vázquez-García and María José Santi-Cano. Lifestyle and Treatment Adherence Intervention after a Coronary Event Based on an Interactive Web Application (EVITE): Randomized Controlled Clinical Trial Protocol. Nutrients 2021, 13, 1818, pp. 1-14. Impact factor: 5.719. Quartile/Decile: Q1/D2 (17/88). INDICATE THE RESEARCH GROUPS THAT PARTICIPATE (IF APPLICABLE): 1) Nutrición: Aspectos biomoleculares, fisiopatológicos, clínicos y sociosanitarios. 2) GADICOR. 3) Epidemiología y Salud Pública.
2. Cuenca Zaldívar, J.N., Calvo, S., Bravo-Esteban, E., Oliva Ruiz, P., Santi-Cano, M.J., Herrero, P. Effectiveness of dry needling for upper extremity spasticity, quality of life and function in subacute phase stroke patients. Acupunct. Med. 2021, 39 (4), pp. 299-308. Impact factor: 2.267. Quartile/Decile: Q3/D6 (17/28). INDICATE THE RESEARCH GROUPS THAT PARTICIPATE (IF APPLICABLE): 1) Nutrición: Aspectos biomoleculares, fisiopatológicos, clínicos y sociosanitarios. 2) Epidemiología y Salud Pública.
3. Rubén Aragón-Martín, María del Mar Gómez-Sánchez, David Jiménez-Pavón, José Manuel Martínez-Nieto, Mónica Schwarz-Rodríguez, Carmen Segundo-Iglesias, José Pedro Novalbos-Ruiz, María José Santi-Cano, José Castro-Piñero, Carmen Lineros-González, Mariano Hernán-García, Amelia Rodríguez-Martín. A multimodal intervention for the prevention of overweight and obesity in schoolchildren. A protocol study “PREVIENE-CÁDIZ”. Int. J. Environ. Res. Public Health. 2021, 18, 1622, pp 1-19. Impact factor: 3.390. Quartile/Decile: Q2/D4 (118/274). INDICATE THE RESEARCH GROUPS THAT PARTICIPATE (IF APPLICABLE): 1) Nutrición: Aspectos biomoleculares, fisiopatológicos, clínicos y sociosanitarios. 2) Epidemiología y Salud Pública.
4. Mondejar, R., Mayor Reyes, M., Melguizo Madrid, E., Cañavate Solano, C., Pérez Ramos, S. Utility of icteric index in clinical laboratories: more than a preanalytical indicator. Biochem Medica. 2021, 31 (2), 020703, pp 1-9. Impact factor: 2.313. Quartile/Decile: Q3/D5 (16/29). INDICATE THE RESEARCH GROUPS THAT PARTICIPATE (IF APPLICABLE): 1) Nutrición: Aspectos biomoleculares, fisiopatológicos, clínicos y sociosanitarios. 2) Epidemiología y Salud Pública.

1. Authors: Santi-Cano MJ, Moreno-Rojas R, Rodríguez-Martín A. Title: Modelo alimentario en Andalucía occidental. Journal: Nutrición Hospitalaria. Year, volume, first and last pages: 2019, 36(1):122-130. Impact factor: 1.497. Quartile/Decile: Q3/ D8.

1. Authors: Moreno-Arellano S, Delgado- de Mendoza J, Santi Cano MJ. Title: Sex disparity persists in the prevention of cardiovascular disease in women on statin therapy compared to that in men. Journal: Nutrition, Metabolism and Cardiovascular Disease. Year, volume, first and last pages: 2018, 28, 810-815. Impact factor: 3.679. Quartile/Decile in the year of publication: Q2/D3.

1. Authors: Santi-Cano, María José; Montilla-Rodríguez, Liliana Marcela; Carroza, María Ángeles; Ruiz-Rodríguez, Félix Alejandro. Title: Novel assay for prothrombotic polyphosphates in plasma reveals their correlation with obesity. Journal: Thrombosis Research. Year, volume, first and last pages: 2016; 144:53-55. Impact factor: 2.650. Quartile/Decile in the year of publication: Q2/D5 (Hematology).

1. Authors: Montilla-Rodríguez, Liliana Marcela; Santi-Cano, María José; Carrozas, María Angeles; Ruiz-Rodriguez, Felix Alejandro. Title: Biomarkers of the prothrombotic state in abdominal obesity. Journal: Nutrición Hospitalaria. Year, volume, first and last pages: 2015; 31 (3): 1059-1066. Impact factor: 1.497. Quartile/Decile in the year of publication: Q3/ D8.
2. Authors: Velazquez-Peña, Francisco De Borja; Sanchez-Morillo, Daniel; Crespo-Miguel, Mario; Astorga-Moreno, Sonia; Santi-Cano, María José; Fernández-Granero, Miguel Angel; León-Jiménez, Antonio. Title: Development and Evaluation of an Automated, Home-Based, Electronic Questionnaire for Detecting COPD Exacerbations. Journal: Journal of Healthcare Engineering. Year, volume, first and last pages: 2015; 6: 705-716. Impact factor: 0.925. Quartile/Decile in the year of publication: Q4/D9.

• TITLE: European Burden of Disease Network (burden-eu). PI: Brecht Devleesschauwer. Collaborator: Mª José Santi Cano. COST (Cooperation in Science and Technology), supported by the European Union (EU) Horizon 2020 Programme. PERIOD OF REALIZATION: 28/10/2019 a 27/10/2023. REFERENCE OR FILE (IF YOU KNOW IT): CA18218.