EM10: Severe Mental Disorder

• Study "Effectiveness of the application of the shared decision-making process (SDT) in the choice of antipsychotic treatment at discharge in hospitalized schizophrenic patients (DECIDE Study)". Project financed in the competitive call of the Ministry of Health 2013 with no. exp. PI-0309-2013. In the context of this Project, the study "Evidence of reliability and validity of the COMRADE scale" is being carried out to assess the satisfaction perceived by the patient regarding their participation in decision-making.
• Study "Determinants of functional capacity in schizophrenia: role of social cognition observable by the main caregiver". Project Financed in the competitive Call of the Ministry of Health 2016 with no. exp. PS-0037-2016. In the context of this Project, the study "Evidence of reliability and validity of the OSCARS scale" is being carried out to assess the social cognition observable by the caregiver. 2 doctoral theses have begun in the context of this project. This study is extended through the Call for Autonomous Communities oriented to the Province (ITI – FEDER Funds). Participating entities: Foundation for the Management of Biomedical Research of Cádiz (FCádiz). Duration: 36 months (January 2018-December 2020).
• Study "DESATA". Prevalence study, description and identification of factors associated with the practice of mechanical restraint in our Mental Health Hospitalization Unit of Jerez.
• Study on satisfaction with treatment and perception of adequacy of buprenorphine/naloxone doses in the treatment of opioid addiction. Collaborative study with the Drug Addiction Unit of the Hospital de la Santa Creu i Sant Pau in Barcelona. Principal investigators: José Pérez de los Cobos (Santa Creu Hospital) and Francisco González Saiz (UGC Mental Health – AGS Norte de Cádiz). Financed by Indivior.

Schizophrenia Mechanical restraint Shared decision making Social cognition Buprenorphine / naloxone

• Principal Investigators:
  • Francisco González Saiz (PI).
  • José María Villagrán Moreno (Co-PI).
• Investigators:
  • Carmen Rodríguez Gómez.
  • Juan Manuel Pascual Paño.
  • José María Mongil San Juan.
  • José Ildefonso Pérez Revuelta.
  • Rocío Torrecilla Olivarrieta.
  • Edgar García Spínola (Trainee Researcher).
  • Anaís López García (Trainee Researcher).
  • Esperanza Vergara Moragues.
  • Leticia Muñoz Manchado.
  • Rafael Quintero Díaz.
  • Joseph J. Cooper (Visiting Researcher).
  • Ignacio Ruz Franzi.
  • Alejandro Pérez Revuelta.
  • Nuria Laherrán Cantera.

• Instituto Nacional de Salud Carlos III, Acción Estratégica en Salud 2017-2020, 2018, PI-18/01691 Co-PI: Francisco González Saiz. Evaluación de la capacidad de modulación cognitiva en estados de depresión y dolor crónico como consecuencia de cambios en la neurogénesis adulta en hipocampo y su correlato con la función del Locus Coeruleus.

• Iniciativa Territorial Integrada (ITI) 2014-2020 para la provincia de Cádiz, por la Consejería de Salud y por el Fondo Europeo de Desarrollo Regional PI-0064-2017. PI: Francisco González Saiz. Papel de la cognición social como factor predictivo del funcionamiento psicosocial del paciente esquizofrénico: Estudio Ecofun.
• Iniciativa Territorial Integrada (ITI) 2014-2020 para la provincia de Cádiz, por la Consejería de Salud y por el Fondo Europeo de Desarrollo Regional PI-0080-2017. Collaboration. Búsqueda de marcadores biológicos en la comorbilidad del dolor crónico y los trastornos afectivos.
• Iniciativa Territorial Integrada (ITI) 2014-2020 para la provincia de Cádiz, por la Consejería de Salud y por el Fondo Europeo de Desarrollo Regional PI-0009-2017. Collaboration. Biomarcadores de la respuesta terapéutica en el trastorno bipolar.
• Consejería de Salud y Familias, Junta de Andalucía, PS-0037-2016. PI: Francisco González Saiz. Factores determinantes de la capacidad funcional en la esquizofrenia: papel de la cognición social observable por la persona cuidadora principal.

1. Pérez-Caballero L, Torres-Sánchez S, Romero López-Alberca C, González-Saiz F, Micó JA, Berrocoso E. Monoaminergic system and depression. Cell and Tissue Research. 2019, 377: 107-113. DOI: 10.1007/s00441-018-2978-8. Q3.

1. Guzmán-Parra J, Aguilera-Serrano C, García-Sanchez JA, García-Spínola E, Torres-Campos D, Villagrán JM, Moreno-Küstner B, Mayoral-Cleries F. Experience coercion, post-traumatic stress, and satisfaction with treatment associated with different coercive measures during psychiatric hospitalization. International Journal of Mental Health Nursing. 2018; doi: 10.1111/inm.12546. Impact factor JCR: 2.033, Q3.
2. Alcaraz S, González-Saiz F, Trujols J, Vergara-Moragues E, Siñol N, Pérez de los Cobos J. 2018. A cluster-analytic profiling of heroin-dependent patients based on level, clinical adequacy, and patient-desired adjustment of buprenorphine dosage during buprenorphine-naloxone maintenance treatment in sixteen Spanish centers. Drug & Alcohol Dependence, 187: 278-284. Impact factor JCR: 3.32, Q1.
3. Pérez de los Cobos J, Trujols J, Alcaraz S, Siñol N, Lozano O, González-Saiz F. 2018. Development and validation of the scale to assess satisfaction with medication for addiction treatment – buprenorphine-naloxone for heroin addiction (SASMAT-BUNHER). International Journal of Drug Policy 58: 126-134. Impact factor JCR: 4.24, Q1.
4. Pérez Revuelta J, Villagrán-Moreno JM, Moreno-Sánchez L, Pascual-Paño J, González-Saiz F. 2018. Patient perceived participation in decision making on their antipsychotic treatment: evidence of validity and reliability of the COMRADE scale in a sample of schizophrenia spectrum disorders. Patient Education and Counselling 101: 1477-1482. Impact factor JCR: 2.78, Q1.
5. González-Saiz F, Lozano Rojas O, Trujols J, Alcaraz S, Siñol N, Pérez de los Cobos J, Buprenorphine Survey Group. 2018. Evidences of validity and reliability of the Opiate Dosage Adequacy Scale (ODAS) in a simple of heroin addicted patients in buprenorphine/naloxone maintenance treatment. Drug & Alcohol Dependence, 183: 127-133. Impact factor JCR: 3.22, Q1.

1. Vergara-Moragues, E., Verdejo-García, A., Lozano, O, Santiago-Ramajo, S., González-Saiz, F., Betanzos Espinosa, P., Pérez García, M. 2017. Association between executive function and outcome measure of treatment in therapeutic community among cocaine dependent individuals. Journal of Substance Abuse Treatment. To link to this article: http://dx.doi.org/10.1016/j.jsat.2017.04.014 . Impact factor: 2,72. Q2.
2. Araos, P., Vergara-Moragues E, González-Saiz F, Pedraz M, García-Marchena, N, Romero P, y Rodriguez de Fonseca. 2017. Differences in the rates of drug polyconsumption and psychiatric comorbidity among patients with cocaine use disorders according to the healthcare attention resource. Journal of Psychoactive Drugs, DOI: 10.1080/02791072.2017.1342151. To link to this article: http://dx.doi.org/10.1080/02791072.2017.1342151. Impact factor JCR: 1.775, Q2.
3. Trujols J, González-Saiz F, Manresa MJ, Alcaraz S, Batlle F, Duran-Sindreu S, Pérez de los Cobos J. 2017. Patient perception of methadone dose adequacy in methadone maintenance treatment: the role of perceived participation in dosage decisions. Patient Education and Counseling, 100, 981-986. JCR. FI: 2, 23. Q2.
4. Perez V, Salavert A, Espadaler J, Tuson M, Saiz-Ruiz J, Sáez-Navarro C, Bobes J, Baca-García E, Vieta E, Olivares JM, Rodríguez-Jiménez R, Villagrán JM, Gascón J, Cañete-Crespillo J, Solé M, Saiz PA, Ibáñez A, de Diego-Adeliño J, AB-GEN Collaborative Group and Menchón JM. Efficacy of prospective pharmacogenetic testing in the treatment of major depressive disorder: results of a randomized, double-blind clinical trial. BMC Psychiatry. (2017) 17:250, DOI 10.1186/s12888-017-1412-1 (FI: 2.613).
5. Vergara-Moragues E, Verdejo-García, A; Lozano, OM ; Santiago-Ramajo , S; González-Saiz F; Betanzos Espinosa P; Pérez García M. (2017) Association between executive function and outcome measure of treatment in therapeutic community among cocaine dependent individuals. Journal of substance abuse treatment, 78, 45-55 doi: 10.1016/j.jsat.2017.04.014. Impact factor JCR: 2.465, Q2

1. Vergara-Moragues, E.; Mestre Pintó, J.; Araos Gómez, P.; Rodríguez-Fonseca, F.; Torrens, M. y González-Saiz, F. (2016). Can symptoms help in differential diagnosis between induced vs independent psychosis in cocaine users? Pyschiatry Research, 242, 94-100. doi:10.1016/j.psychres.2016.05.043. Impact factor JCR: 2.467 .Q2.
2. Rubio-Valera M, Huerta-Ramos E, Baladón L, Aznar-Lou I, Ortiz-Moreno JM, Luciano JV, Roset-Arisso PN, Salvador-Carulla L, Villagrán JM, Mayoral F, Gracia A, Serrano-Blanco A. Qualitative study of the agitation states and their characterization, and the interventions used to attend them. Actas Esp Psiquiatr. 2016 Sep; 44(5):166-77. Impact factor JCR: 1.2. Q3.

1. Vélez-Moreno A, González-Saiz, F, Rojas AJ, Torrico-Linares E, Fernández-Calderón F, Ramírez-López J, Lozano OM. 2015. Reliability and validity of the spanish versión of the Substance Abuse Severity Scale. European Addiction Research, 21, 39-46. FI JCR: 2,1. Q3.
2. Vélez-Moreno A, Lozano OM, Fernández-Calderón F, Rojas AJ, Sayans-Jimenez P, González-Saiz F, Ramirez López J. Evidencias de validez, sensibilidad y especificidad de la dimensión de gravedad de la dependencia del alcohol de la SDSS. Actas Española de Psiquiatría 2015; 43 (3): 99-108. Impact factor JCR: 1,2. Q3.

1. Vergara-Moragues E., Araos Gómez P., González-Saiz, F & Rodríguez-Fonseca, F (2014) Cocaine-induced psychotic symptoms in clinical setting. Psychiatry Research, 217 (1-2):115-120. doi: 10.1016/j.psychres.2014.02.024. Impact factor JCR: 2.466. Q2.