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EM7: Metabolic and Bariatric Surgery: Clinical Studies and Experimental Models

Clinical and basic multidisciplinary group oriented to the study of fatty liver disease and type II diabetes, and the mechanisms involved in the impact on both entities of the different bariatric surgery techniques. Oriented to the human clinic and with the development of experimental lines in animals.

Responsible researcher
  • J. Arturo Prada-Oliveira:
    • E-mail: arturo.prada@uca.es.
    • ORCID: 0000-0001-8401-1441.
Co-responsible researcher
  • José Manuel Pacheco García:
    • E-mail: pachecadiz2@gmail.com.
    • ORCID: 0000-0001-7734-3894.
Lines of research
  • Consequences of bariatric surgery techniques on metabolic syndrome and inflammatory status in obese patients.
  • Surgical techniques of metabolic consequences in humans: resolution of obesity; improvement of the techniques used; social implications and improvement of quality of life.
  • Experimental surgery in animal models for the study of the metabolic consequences of bariatric surgery.
  • Compensatory metabolic mechanisms in the chronic development of type 2 Diabetes mellitus, through the analysis of the involvement of peripheral tissues in the management of hydrocarbon metabolism.
  • Pathogenesis of Diabetes mellitus and molecular biology of related metabolic mechanisms.
  • Evolution and development of nonalcoholic fatty liver disease. Conditioning on the resolution of T2DM after bariatric surgery. Preconditioning to hepatocarcinoma.
Keywords
Surgery Bariatric surgery Experimental surgery Diabetes mellitus type 2 EHDGNA Pancreas
Responsible researcher
J. Arturo Prada-Oliveira
Full Professor of University.
  • E-mail: arturo.prada@uca.es.
  • ORCID: 0000-0001-8401-1441.
  • Research ID: H-3796-2017.
Co-responsible researcher
José Manuel Pacheco García
UGC of Surgery HU Puerta del Mar.
  • E-mail: pachecadiz2@gmail.com.
  • ORCID: 0000-0001-7734-3894.
Members of the Team
  • Responsible Researchers:
    • J. Arturo Prada-Oliveira (PI).
    • José Manuel Pacheco-García (Co-IR).
  • Researchers:
    • Gonzalo Pérez-Arana.
    • Isabel Mateo-Gavira.
    • Alonso Camacho-Ramirez.
    • Mª Ángeles Mayo-Ossorio.
    • María Jesús Castro Santiago.
    • David Almorza-Gomar (R3A1).
    • Manuel Macías-Rodríguez.
    • Amparo Valverde Martínez.
    • María Dolores Casado Maestre.
  • Predoctoral Researchers:
    • E. Sancho Maraver.
    • Jesús Salas-Álvarez.
    • Susana Roldán Ortiz.
    • F.J. Campos-Martínez.
    • A. Bengoechea Trujillo.
National Calls
  • MINISTRY OF ECONOMY AND COMPETITIVENESS, Research Project, Challenges of the Society, 2015 CTM 2015-70731-R. PI: David Almorza Gomar. Integration of omics tools for environmental risk assessment of emerging contaminants in marine species of commercial interest.
Publications 2021
  1. Bancalero, Jose; Camacho-Ramirez, Alonso; Fernández-Vivero, José; Ribelles-García, Antonio; Mayo, Mª De Los Ángeles; Almorza-Gomar, David; Prada-Oliveira, José Arturo; Pérez-Arana, Gonzalo. GLUCAGON-PRODUCING CELL EXPANSION IN WISTAR RATS. CHANGES TO ISLET ARCHITECTURE AFTER SLEEVE GASTRECTOMY. Obesity Surgery. 2021. 31, pp. 2241-2249. Q1 JCR. FI 4.129 (2020). PAIDI CTS1079. INIBICA affiliation compliant.
  2. Pérez-Arana, Gonzalo; Fernández-Vivero, José; Camacho-Ramirez, Alonso; Díaz, Alfredo Luis; Bancalero, Jose; Ribelles-García, Antonio; Almorza-Gomar, David; Carrasco-Molinillo, María Del Carmen; Prada-Oliveira, José Arturo. Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet. Journal of Clinical Medicine. 2021. 10, pp. 4217-4225. Q1 JCR. 4.242 (2020). PAIDI1079. INIBICA affiliation compliant.
  3. Mateo-gavira, Isabel; Mª de los Ángeles Mayo Ossorio; José Manuel Pacheco Garcia; Prada-Oliveira, José Arturo; FCO JAVIER VILCHEZ LOPEZ. Evaluation of Clinical Factors Predictive of Diabetes Remission Following Bariatric Surgery. Journal of Clinical Medicine. 2021. 10, pp 1045. Q1 JCR. 4.242 (2020). PAIDI1079. https://doi.org/10.3390/jcm10091945. INIBICA affiliation compliant.
  4. Almorza-Gomar, David; Prada-Oliveira, José Arturo; Kandús, Maria; Salerno, Juan Carlos. An example to teach Markov chains and Hardy-Weinberg equilibrium through Mendel's laws. Journal of biological education. 2021. 55. Q4 JCR (2020). https://doi.org/10.1080/00219266.2021.1905688.
  5. Ribelles-García, Antonio; Carrasco-Molinillo, María Del Carmen; Almorza-Gomar, David; Camacho-Ramírez, Alonso; Pérez-Arana, Gonzalo; Prada-Oliveira, José Arturo. BODY PAINTING AS A USEFUL TECHNIQUE IN TEACHING ANATOMY FOR SCIENCES OF PHYSICAL ACTIVITY AND SPORTS STUDENTS. https://doi.org/10.1080/00219266.2021.1905688. 2021. 16, pp. 5-7. Q4 JCR (2020).
Publications 2019
  1. AuthorsJosé Arturo Prada Oliveira; Alonso Camacho Ramirez; Jesús María Salas Álvarez; Francisco Javier Campos-Martínez; Alfonso Maria Lechuga Sancho; David Almorza Gomar; Gonzalo Pérez Arana. Title GLP-1 mediated improvement of the glucose tolerance in the T2DM GK rat model after massive jejunal resection. Annals of Anatomy. Year, volume, first and last pages 2019, 223, 1-7. Quartile/decile in year of publication Q2.
  2. AuthorsAlonso Camacho Ramirez; David Almorza Gomar; Alfredo Diaz Gomez; Isabel Mateo Gavira; Macias-Rodriguez, Manuel; Gonzalo Pérez Arana; José Arturo Prada Oliveira. Title The histomorphometric parameters of endocrine pancreas after bariatric surgery in healthy animal models. Tissue and Cell Journal. Year, volume, first and last pages 2019, 57 (4), 78 - 83. http://doi.org/10.1016/j.tice.2019.02.008. Quartile/decile in publication year Q3.
  3. AuthorsDavid Almorza Gomar; Virginia-Kandus, Mariana; José Arturo Prada Oliveira; Salerno, Juan Carlos. Title Teaching Application of Markov Chains: Method of Determining the Prevalence of a Linkage System in Population Genetic. Human Heredity Journal. Year, volume, first and last pages 18 - 83, pp. 225 - 226. 2019. Quartile/decile in publication year Q4.
  4. Authors: María Del Carmen Carrasco Molinillo; Antonio Ribelles García; David Almorza Gomar; Gonzalo Pérez Arana; José Arturo Prada Oliveira. Title The Teaching of Surface Anatomy by Body Painting. International Journal of Morphology. Year, volume, first and last pages 2019, 37 (3), 912 - 916. Quartile/decile in year of publication Q4.
  5. AuthorsPinto-Souza, Ana Rosa Wakim; Gonzalo Pérez Arana; Firetto-Saladino, Chiara; María Del Carmen Carrasco Molinillo; Antonio Ribelles García; José Arturo Prada Oliveira. Title A classical model of educational cooperation in Human Anatomy: The Table Chieftains. Folia Morphologica Journal. Year, volume, first and last pages 2019, 78, In press, accepted. Available online at: https://www.scimagojr.com/journalsearch.php?q=15091&tip=sid>. Quartile/decile in year of publication Q4.
  6. Authors: Joshua Falckenheiner-Soria, José Bancalero-De Los Reyes, Alejandra Moreno-Arciniegas, Alonso Camacho-Ramírez, JArturo Prada-Oliveira, Gonzalo M Pérez-Arana. Title The controversial involvement of glp-1 in physiological mechanisms triggered after bariatric surgery. Journal: International Journal of Morphology. Year, volume, first and last pages 2019, 37(1). Quartile/decile in year of publication Q4.
  7. AuthorsAlejandra Moreno-Arciniegas, Joshua Falckenheiner-Soria, José Bancalero-De Los Reyes, Alonso Camacho-Ramírez, María de los Angeles Mayo-Ossorio, J Manuel Pacheco-García, Gonzalo M Pérez-Arana and J Arturo Prada-Oliveira. Title The main participation of the enterohormone glp-1 after bariatric surgery. Journal: Minerva Chirurgica. Year 2019, 74(1): 7-13. DOI: 10.23736/S0026-4733.18.07681-2. Quartile/decile in year of publication Q4.
Publications 2018
  1. AuthorsDavid Almorza Gomar; Kandús, Maria; Salerno, Juan Carlos; José Arturo Prada Oliveira. Title The genotype by environment interaction (G×E) inbred lines and hybrids of maize. Journal: Genetic Epidemiology. Year, volume, first and last pages 2018, 42, 685-686. Quartile/decile in year of publication Q1.
Publications 2017
  1. AuthorsBaena-Nieto G, Lomas-Romero IM, Mateos RM, Leal-Cosme N, Perez-Arana G, Aguilar-Diosdado M, Segundo C, Lechuga-Sancho AM. Title: Ghrelin mitigates β-cell mass loss during insulitis in an animal model of autoimmune diabetes mellitus, the BioBreeding/Worcester rat. Journal: Diabetes Metab Res Rev. Year, volume, pages first and last 2017; 33(1). doi: 10.1002/ dmrr.2813. Epub 2016 Jun 14. Quartile/decile in year of publication Q2.
  2. AuthorsJ Falckenheiner-Soria, A. Camacho, A Moreno, G Perez Arana, JA Prada-Oliveira. Title The impact of the bariatric surgery in pancreatic beta cell population in wistar rat models. Journal: Surg Endosc. Year, volume, pages first and last 2017; 31: 42-44. Quartile/decile in year of publication Q1.
  3. Authors: Camacho-Ramírez A, Blandino-Rosano M, Segundo-Iglesias MC, Lechuga-Sancho AM, Aguilar-Diosdado M, Pérez-Arana GM, Prada-Oliveira JA. Title Bariatric surgery influences β-cell turnover in non-obese rats. Journal Histology and Histopathology. Year, volume, pages first and last 2017; 32: 1341-1350. Quartile/decile in year of publication Q2.
  4. Authors: Isabel Mateo Gavira; Francisco Javier Vílchez López; María Victoria García Palacios; Florentino Carral San Laureano; Francisco Manuel Visiedo García; Manuel Aguilar Diosdado. Title Early blood pressure alterations are associated with pro-inflammatory markers in type 1 diabetes mellitus. Journal J Hum Hypertens. Year, volume, pages first and last 2017; 31: 151 - 156. quartile/decil in year of publication Q3.
  5. Authors: JA Prada-Oliveira, D Almorza-Gomar, J Falckenheiner-Soria, A Moreno- Arciniegas, A Camacho-Ramírez, G Pérez-Arana.Title: The stressed pancreas determines the islet cells to encode the glucagon-like peptide 1 receptor with bariatric surgery used as functional stressful factor. Journal: Genetic epidemiology. Year, volume, pages first and last 2017; 10.1002/gepi.22062 . [Epub]. Quartile/decile in year of publication Q1.
Publications 2016
  1. Authors: Pinto-Souza AR, Firetto C, Pérez-Arana G, Lechuga-Sancho AM,Prada-Oliveira JA. Title Differences in the estrous cycles of Goto-Kakizaki and Wistar rats. Journal: LAB Animal. Year, volume, first and last pages 2016 45(4):143-148. Quartile/decile in year of publication Q4.
  2. AuthorsMayo Ossorio, Mª De Los Ángeles. Title A 49-year-old woman with abdominal pain and constipation of 24 hours of evolution. Journal: MEDICINE. Year, volume, first and last pages 2016; 12: 406e1-406e4. Quartile/decile in year of publication Q2.
  3. AuthorsIsabel Mateo Gavira; Francisco Javier Vílchez López; María Victoria García Palacios; Florentino Carral San Laureano; Soledad Jiménez Carmona; Manuel Aguilar Diosdado. Title Nocturnal blood pressure is associated with the progression of microvascular complications and hypertension in patients with type 1 diabetes mellitus. Journal: Journal of Diabetes and Its Complications. Year, volume, pages first and last 2016; 30: 1326 - 1332. Quartile/decile in year of publication Q3.
  4. Authors: Laura Larrán Escandón; Isabel Mateo Gavira; Francisco Javier Vílchez López; Efraim Gómez Cárdenas; Manuel Aguilar Diosdado. Title Pituitary apoplexy as presentation of atypical teratoid/rhabdoid tumor in an adult. Journal: Endocrinol Nutr. year, volume, pages first and last 2016; 63: 364 - 365. Quartile/decile in year of publication Q4.
  5. AuthorsMayo Ossorio, Mª De Los Ángeles. Title Acute Abdomen. Journal: Medicine. Year, volume, first and last pages 2016; 12: 363-379. Quartile/decile in year of publication Q2.
  6. AuthorsMayo Ossorio, Mª De Los Ángeles. Title Intestinal ileus. Journal: Medicine. Year, volume, first and last pages 2016; 12: 346-362. Quartile/decile in year of publication Q2.
Publications 2015
  1. Authors:: Pacheco, José Manuel; Mayo, Mª De Los Ángeles. Title Fulminant hepatic failure in patients undergoing gastric bypass for morbid obesity. Journal: Nutrición Hospitalaria. Year, volume, pages first and last 2015; 32: 430-434. Quartile/decile in year of publication Q3.
  2. Authors:: Pérez-Arana G, Camacho-Ramírez A, Segundo-Iglesias MC, Lechuga-Sancho AM, Sancho-Maraver E, Aguilar-Diosdado M, Prada-Oliveira JA. Title A surgical model of short bowel syndrome induces a long-lasting increase in pancreatic beta-cell mass. Journal: Histology and Histopathology. Year, volume, pages first and last 2015 Apr;30(4):479-87. doi: 10.14670/HH-30.479. epub 2014. Quartile/decile in year of publication Q2.