Objective
The PERSUADE project aims to improve rhythm control therapy for AF by better understanding the differences in the atrial fibrotic substrate between men and women, and patients with and without cardiovascular comorbidities. Parameters such as conduction velocity, functional mapping, surface ECG, and markers from cardiac CT scans can provide a deeper understanding of the arrhythmogenic substrate and guide treatment based on catheter ablation. In addition, computer models and machine learning techniques can be used to explore underlying mechanisms and predict the prognosis of patients undergoing AF treatment. The ultimate goal is to automate treatment strategies and improve outcomes for AF patients through a better understanding of fibrosis formation and its underlying mechanisms.
Core components
Open science
Transparent sharing of research findings, effective research output management, reproducibility of research outputs, open access to research outputs, stakeholders involvement.
Multidisciplinary team
Synergistic, strong and effective consortium that features highly experienced experts in electrophysiology, imaging, AI, and modeling, comprising universities, hospitals, and patient associations from 4 different countries
Responsible Research and Innovation
Research responds to the social and cultural context, and ensure that results are translated into treatments that are accessible and affordable for all population groups, particularly those from marginalized communities.
Consortium
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This project has received funding from the European Union under the umbrella of the Partnership Fostering a European Research Area for Health (ERA4Health) (GA°101095426 of the EU Horizon Europe Research and Innovation Programme)
National and regional funding organizations
