Consortium
The PERSUADE consortium fosters transnational collaboration mainly at three different levels: by promoting cross-organization data collaborations, which contribute to larger data-sets that consider demographic heterogeneity; by developing decision-support tools and platforms directly integrated in medical practice and accessible for hospitals with varying resources; by promoting privacy-preserving technologies that enable cross-organization analysis.
This is a highly synergistic, strong and effective consortium that features highly experienced experts in electrophysiology, imaging, AI, and modeling, as PERSUADE comprises universities, hospitals, and patient associations from 4 different countries. This multidisciplinary effort will enable the acquisition of a large multimodal dataset from various centers that will be homogenized, structured, and labeled following standardized guidelines for the characterization of the left atrial substrate.
PERSUADE Coordinator
Clinical partner
Coordinator WP5,WP6
Principal investigator:
Etelvino Silva García, has undertaken research projects in the field of cardiology from an engineering perspective for over 15 years. Research tasks have focused on both electrical and mechanical analysis of various cardiac pathologies based on multimodal medical imaging and signals.
Saman Golmaryami is a researcher in Bioinformatic, Biomedical and Neuroscience Engineering. Saman has studied biomedical engineering as a bachelor’s and bioinformatics as a master’s student. During his studies, he has worked on several projects in the field of biomedical engineering and mathematical modelling. With expertise and knowledge in signal processing and programming with Python, he is working on data collection and feature extraction from the signals to train a reliable model to automate the treatment strategy of AF patients.
Clinical partner
Coordinator WP1,WP4
Principal Investigator:
Prof. Dr. Joris R. de Groot, his research focuses on understanding the arrhythmogenic mechanism of AF and using this knowledge to improve patient treatment. Over the past years, he has initiated one of the largest thoracoscopic AF ablation research programs in the world, resulting in the publication of the largest randomized trial in the field recently.
Dr. Nerea Arrarte Terreros is a postdoctoral researcher at the Amsterdam University Medical Centers and Universitat Pompeu Fabra. With a background in physics, her academic life is focused on translational research, aiming to solve biomedical and clinical problems. As part of her current postdoc position, she focuses on the interplay between atrial fibrillation and stroke, studying the added value of quantitative imaging and computer-modelling markers in predicting treatment and patient outcome.
Clinical partner
Supporting WP1, WP2, WP3, WP4, WP5, WP6
Principal Investigators:
Radu-Gabriel VĂTĂȘESCU, Assoc. Prof., MD, PhD, his research focuses on clinical cardiology, invasive cardiac electrophysiology and cardiac implantable electronic devices focused on complex atrial arrhythmia mapping and ablation, malignant ventricular arrhythmia mapping and ablation in structural heart disease, intraprocedural substrate imaging, cardiac resynchronization therapy and conduction system pacing.
Laura Stanciulescu, MD is a cardiologist and
PhD candidate specializing in personalized treatment strategies for ventricular
arrhythmias in patients with structural heart disease, with a focus on
AI-driven data analysis. She is actively involved in several research projects
aimed at the early diagnosis and management of cardiac arrhythmias. Her primary
research interests encompass clinical cardiology, cardiac electrophysiology,
and cardiac implantable electronic device (CIED) procedures.
University partner
Coordinator WP2
Principal Investigator:
Jose Felix, Rodriguez Matas, Assoc. Prof., PhD, mechanical engineer from the Universidad Simón Bolívar, Venezuela, with a Ph.D. degree in mechanical engineering from the University of Notre Dame, IN, in 1999. He is responsible for the Computational Biome- chanics Laboratory at the Department of Chemistry, materials and chemical engineering “Giulio Natta” at Politecnico di Milano. His current research interests include vascular biomechanics and cardiac electrophysiology with emphasis on the mathematical modeling applied to understand the mechanisms underlying cardiac arrhythmias.
Chiara Celotto earns a Master’s degree Civil Engineering and a PhD in Biomedical Engineering. Her research has been focused on biomedical signal analysis, on the numerical simulation of cardiac electrophysiology, particularly investigating the role of the autonomic nervous system in the initiation and maintenance of atrial fibrillation. Currently, she is a postdoctoral researcher at the Politecnico di Milano, developing detailed 3D computational models of the heart to investigate how substrate and pharmacological therapies influence the outcomes of atrial fibrillation ablation.
University partner
Coordinator WP3
Principal Investigator:
Miguel Rodrigo Bort, PDI-Ajudant Doctor/A, is a biomedical engineer with extensive experience in developing non-invasive technologies for the diagnosis and treatment of cardiac arrhythmias, especially atrial fibrillation. His research focuses on characterizing the underlying mechanisms of these arrhythmias and developing new therapeutic tools. He has a solid academic background and has conducted research stays at prestigious institutions such as the University of Michigan and Stanford. Additionally, he is the founder of two technology-based companies focused on cardiovascular health.
CSO partner
Supporting WP1, WP2, WP3, WP4, WP5, WP6
Role within the consortium:
Patient association carrying the voice and the desire of patients on the centre of the project, involved in co-creating communication activities and the development of good practices to inform about AI-assisted health treatments in public health care systems. We will also help to maximise the visibility and expected impacts of the project at both local and European level from our societal role of patient association.
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This project has received funding from the European Union under the umbrella of the Partnership Fostering a European Research Area for Health (ERA4Health) (GA°101095426 of the EU Horizon Europe Research and Innovation Programme)
National and regional funding organizations
