CO10: Molecular Immunology and Gene and Cell Immunotherapy
The group is dedicated to research in immunology, with a special emphasis on the development of chimeric antigen receptors (CAR) for cellular immunotherapy and the study of early signaling mechanisms and mechanisms involved in the induction of immune tolerance.
Responsible researcher
- Francisco José García Cózar:
- E-mail: curro.garcia@uca.es
- ORCID: 0000-0003-3720-259x
Lines of research
- Line 1: Molecular mechanisms of immune tolerance induction. Genomic and proteomic analysis of the mechanisms responsible for basic immune tolerance and those responsible for the development of chronic infections.
- Line 2: Gene and Cell Immunotherapy. Fundamentally based on the development of Chimeric Antigen Receptors (CAR), with applications in oncological and inflammatory diseases (cardiovascular, digestive, neurological, etc.) and in transplant organ rejection.
- Línea 3: Nanomedicina. Desarrollo de contrastes basados en nanopartículas para la identificación especifica de moléculas in vivo, para aplicaciones en Diagnóstico por Imagen.
- Line 4: Early intracellular signaling in T and B lymphocytes. Implications in immunological pathologies.
- Line 5: Transmembrane adapter proteins and their role as regulators of activation in lymphocytes.
Keywords
- # T lymphocytes
- # Immunological Tolerance
- # Intracellular signaling
- # Membrane adapter proteins
- # Cardiovascular disease
- # Gene immunotherapy
- # Cellular immunotherapy
- # Nanoparticles
Responsible researcher
Francisco José García Cózar:
University professor.
- E-mail: curro.garcia@uca.es
- ORCID: 0000-0003-3720-259x
- Research ID: A-6212-2013
Team Members
- Principal Investigators:
- Francisco José García Cózar (PI).
- Researchers:
- Ana Diez Núñez.
- Auxiliadora Mazuecos Blanca.
- Juan Carlos Bohórquez Sierra.
- Carmen Mínguez Mañanes.
- Carmen María Pérez Alberca.
- Cristina Montes Durán.
- Encarnación García Domínguez.
- Federico Rodríguez-Rubio Cortadelas.
- Jesus Garcia Serrano.
- Jesus Navarro Navarro.
- Juan Carlos Pérez Herrera.
- María Isabel Moreno García.
- Teresa Maria Garcia Alvarez.
- Juan Pedro Muñoz Miranda.
- Ricardo Fernández Cisnal.
- Javier Álvarez Medialdea.
- Lucia Olvera Collantes.
- Sebastián Garzón López.
- María Victoria Verdugo Cabeza de Vaca.
- Noelia del Carmen Moares Fernández.
- Antonio Gabucio Lopez.
Networks
This groupactively participates in the following Networks:
CINNAMON COST Action
Visita la web: https://cinnamon-costaction.eu/