CO12: Neuroimaging and Psychophysiology

The group is a multidisciplinary team led by a Ramón y Cajal researcher and composed of various pre- and postdoctoral researchers and clinical researchers, including psychologists, biologists, specialists in clinical neuroscience, as well as a large group of neurologists and neurosurgeons. The group’s overall objective is to study the biological basis and brain mechanisms responsible for the pathological symptoms in various neurological diseases, such as Parkinson’s disease, multiple sclerosis, and chronic migraine, among others. To this end, the researchers use innovative tools and cutting-edge methodologies, including high-density EEG recordings, intracranial recordings in patients, peripheral measurements such as eye tracking, advanced analysis of structural or functional MRI, as well as various brain stimulation techniques, including transcranial magnetic stimulation and deep brain stimulation.

Responsible researcher

Javier Jesús González Rosa:
- E-mail: javier.rosa@uca.es
- ORCID: 0000-0002-5609-1103

Lines of research

Line 1: Human cognition and cognitive decline.

╸ Assessment of the neural basis of cognitive processes (e.g., executive functions, attention) using electrophysiological and neuroimaging techniques; Design of new cognitive tasks.

╸ Study of the brain mechanisms underlying cognitive function in both healthy individuals and patients with neurological and psychiatric disorders.

╸ Assessment of brain activity patterns and their relationship to the presence of cognitive impairment and clinical abnormalities.

╸ I am currently working with patients who have Parkinson's disease, multiple sclerosis, dementia, obsessive-compulsive disorder, and chronic migraine.

Line 2: Brain imaging methods.

╸ EEG and ERP: Advanced use of electrophysiological analysis and techniques; use of high-density EEG equipment to understand the spatiotemporal dynamics of cortical Networks activation at rest and during cognitive tasks, in both healthy and pathological populations.

╸ New analyses and methodological solutions for localizing brain generators using toolboxes such as Analyzer, EEGLAb, SPM12, and Brainstorm.

╸ Analysis of structural (MRI) and functional (fMRI) neuroimaging data.

╸ Fusion and multimodal integration of electrophysiological (EEG) and hemodynamic (fMRI) data acquired separately or simultaneously.

╸ Intracranial recordings (icEEG) in humans after surgery.

╸ Biometric data collection using “iMotions”: automatic recognition of facial emotions, peripheral activity, and eye tracking.

Line 3: Neuromodulation.

╸ Use of various neuromodulation techniques, such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and transcranial static magnetic stimulation (tSMS), in healthy subjects and those with neurological disorders.

╸ Deep Brain Stimulation (DBS) in Neurological and Psychiatric Patients.

╸ Simultaneous EEG co-recording during TMS and DBS protocols.

Keywords

# Electroencephalography (EEG)
# Structural and Functional Magnetic Resonance Imaging
# Neurological Disorders
# Cognitive Decline
# Neuromodulation and Deep Brain Stimulation (DBS)
# Localization of cortical generators
# Functional Connectivity

CO12: Neuroimaging and Psychophysiology

Responsible researcher

Javier Jesús González Rosa:

Full Professor, University of Cádiz.

E-mail: javier.rosa@uca.es
ORCID: 0000-0002-5609-1103
Research ID: K-1291-2014

Members of the Team

Principal Investigators:
- Javier González Rosa (PI).
Researchers:
- Jesús Riqué Asleep.
- Lucía Forero Díaz.
- Raúl Espinosa Rosso.
- Raúl Rashid López.
- Álvaro Javier Cruz Gómez.
- Esteban Sarrias Arrabal.
- Paloma Macías García.
- Florencia Soledad Sanmartino Balog.
- Fátima Cano Cano.
- Mónica García Corrales.
- Rocío Martínez Regueiro.
- María Melcón Martín.