Line 1: Implant-associated infections. Study of infections associated with joint prostheses, osteosynthesis devices, or cardiovascular devices (pacemakers, implantable defibrillators, etc.). Both descriptive and analytical studies of these types of infections will be conducted, with the aim of identifying risk factors for the development of these infections and prognostic factors for their course.

Line 2: HIV infection. Multicenter studies on the various epidemiological and clinical characteristics of these patients, as well as studies on the efficacy of the various treatment regimens used.

Line 3: Optimization of antimicrobial treatments. Analysis of the results obtained from the “Rational Use of Antibiotics” programs implemented at various hospitals.

Line 4: Hospital-Acquired Bacteremia. Descriptive and analytical studies on hospital-acquired bacteremia.

Line 5: Diabetic Foot Infection. Analysis of the cohort of patients treated by the Diabetic Foot Unit at the Puerto Real University Hospital.

Line 6: Psychosocial and neuropsychological consequences of infectious diseases and associated conditions, with a special focus on substance use and abuse.

Line 7: Assessment of health outcomes using PROMs in individuals with infectious diseases or at risk of developing them and associated conditions, with a particular focus on substance use and abuse.

Line 8: Analysis of gender inequalities in infectious diseases and their comorbidities, with a special focus on substance use and abuse.